Week 10 Post 2

When someone refers to metabolism in medicinal chemistry terms, they are not referring to the number of calories burned at rest, or the use and replacement of organic material in the body. The are referring to the methods of how a drug is removed from the body. When a drug is taken by someone, it enters the bloodstream and is transported to other part of the body. Then, the body want to get rid of it, as its a foreign substance the body doesn't recognize. It does so by one or more chemical reactions to make it less possible to mix in with the plasma and then easier to filter by the kidneys.

 How the drug is metabolized and what the body changes the initial substance to is very important for the safety of drugs. If the drug metabolizes to something extremely dangerous and toxic, and doesn't  metabolized again to something else that drug cant be given. this just another thing that must be considered and another challenge that must be overcome.

Comments

  1. Ms. DunleyNovember 14, 2017 at 5:52 AM

    How does a drug company know how each person wil metabolize the drug?

    ReplyDelete
    Replies
    1. UnknownDecember 14, 2017 at 6:12 PM

      There are a set amount of enzymes the body can produce, and chemists can test the drug in an assay or test tube style test to see how a drug responds to certain enzymes.

      Delete

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